PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23680741-9 2013 In addition to the expected benefits associated with limiting insulin dose and regimen complexity, the specific advantages the DPP-4 inhibitor drug class on hypoglycemia and weight gain could justify combining DPP-4 inhibitors with insulin; additionally, a DPP-4 inhibitor may be of special value to decrease glycemic excursions that are not properly addressed by basal insulin therapy and metformin use, even after optimizing titration of the basal insulin. Metformin 390-399 dipeptidyl peptidase 4 Homo sapiens 127-132