PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23653048-6 2013 In the MLH1-proficient cells SN-38, the active metabolite of irinotecan, induced lower levels of DNA damage than in MLH1-deficient cells, as shown by the weaker induction of gamma-H2AX and p53 phosphorylation. Irinotecan 29-34 tumor protein p53 Homo sapiens 189-192 23653048-6 2013 In the MLH1-proficient cells SN-38, the active metabolite of irinotecan, induced lower levels of DNA damage than in MLH1-deficient cells, as shown by the weaker induction of gamma-H2AX and p53 phosphorylation. Irinotecan 61-71 tumor protein p53 Homo sapiens 189-192