PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23620183-1 2013 We investigated the difference in the effect of synthetic lipid A compounds on MyD88-dependent and -independent Toll-like receptor 4 (TLR4) signaling in mouse macrophage cells. Lipid A 58-65 myeloid differentiation primary response gene 88 Mus musculus 79-84 23620183-3 2013 A maximum level of NF-kappaB activation, which is involved in IL-1beta gene transcription, was also induced to a similar level by these four lipid A compounds, while the maximum level of IFN-beta promoter activity induced during MyD88-independent signaling was also less than 50% for lipid IVa stimulation compared with other lipid A compounds. Lipid A 141-148 myeloid differentiation primary response gene 88 Mus musculus 229-234