PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23606279-6 2013 Our results showed that the interaction of activated monocytes with SMC determines: (i) phosphorylation of STAT3 and reduction of SOCS3 expression in both cell types; (ii) intracellular ROS production dependent on NADPH oxidase (by increased Nox1 expression) and STAT3 activation in SMC; (iii) up-regulation of resistin expression in monocytes dependent on STAT3 activation. Reactive Oxygen Species 186-189 NADPH oxidase 1 Homo sapiens 242-246 23606279-6 2013 Our results showed that the interaction of activated monocytes with SMC determines: (i) phosphorylation of STAT3 and reduction of SOCS3 expression in both cell types; (ii) intracellular ROS production dependent on NADPH oxidase (by increased Nox1 expression) and STAT3 activation in SMC; (iii) up-regulation of resistin expression in monocytes dependent on STAT3 activation. Reactive Oxygen Species 186-189 signal transducer and activator of transcription 3 Homo sapiens 263-268 23606279-6 2013 Our results showed that the interaction of activated monocytes with SMC determines: (i) phosphorylation of STAT3 and reduction of SOCS3 expression in both cell types; (ii) intracellular ROS production dependent on NADPH oxidase (by increased Nox1 expression) and STAT3 activation in SMC; (iii) up-regulation of resistin expression in monocytes dependent on STAT3 activation. Reactive Oxygen Species 186-189 resistin Homo sapiens 311-319 23606279-6 2013 Our results showed that the interaction of activated monocytes with SMC determines: (i) phosphorylation of STAT3 and reduction of SOCS3 expression in both cell types; (ii) intracellular ROS production dependent on NADPH oxidase (by increased Nox1 expression) and STAT3 activation in SMC; (iii) up-regulation of resistin expression in monocytes dependent on STAT3 activation. Reactive Oxygen Species 186-189 signal transducer and activator of transcription 3 Homo sapiens 263-268 23606279-7 2013 Furthermore, exposure of SMC to resistin induces ROS by increasing NADPH oxidase activity and the p22phox and Nox1 expression. Reactive Oxygen Species 49-52 resistin Homo sapiens 32-40 23606279-7 2013 Furthermore, exposure of SMC to resistin induces ROS by increasing NADPH oxidase activity and the p22phox and Nox1 expression. Reactive Oxygen Species 49-52 cytochrome b-245 alpha chain Homo sapiens 98-105 23606279-7 2013 Furthermore, exposure of SMC to resistin induces ROS by increasing NADPH oxidase activity and the p22phox and Nox1 expression. Reactive Oxygen Species 49-52 NADPH oxidase 1 Homo sapiens 110-114 23606279-8 2013 In conclusion, the cross-talk between SMC and monocytes activates STAT3 transcription factor and lead to resistin up-regulation in monocytes and ROS production in SMC. Reactive Oxygen Species 145-148 signal transducer and activator of transcription 3 Homo sapiens 66-71 23606279-9 2013 Moreover, resistin increases the ROS levels in SMC. Reactive Oxygen Species 33-36 resistin Homo sapiens 10-18