PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23408095-3	2013	Most of what is known about how LPS is recognized by the TLR4-MD-2 receptor complex on animal cells has been studied using Escherichia coli lipid A, which is a strong agonist of TLR4 signaling.	Lipid A	140-147	toll like receptor 4	Homo sapiens	57-61	
23408095-3	2013	Most of what is known about how LPS is recognized by the TLR4-MD-2 receptor complex on animal cells has been studied using Escherichia coli lipid A, which is a strong agonist of TLR4 signaling.	Lipid A	140-147	toll like receptor 4	Homo sapiens	178-182	
23408095-4	2013	Recent work from several groups, including our own, has shown that several important pathogenic bacteria can modify their LPS or lipid A molecules in ways that significantly alter TLR4 signaling to NFkappaB.	Lipid A	129-136	toll like receptor 4	Homo sapiens	180-184	
23408095-7	2013	In this review, we provide an overview of lipid A variants from several human pathogens, how the basic structure of lipid A is recognized by mouse and human TLR4-MD-2 receptor complexes, as well as how alteration of this pattern affects its recognition by TLR4 and impacts the downstream immune response.	Lipid A	116-123	toll like receptor 4	Homo sapiens	157-161	
23408095-7	2013	In this review, we provide an overview of lipid A variants from several human pathogens, how the basic structure of lipid A is recognized by mouse and human TLR4-MD-2 receptor complexes, as well as how alteration of this pattern affects its recognition by TLR4 and impacts the downstream immune response.	Lipid A	116-123	toll like receptor 4	Homo sapiens	256-260