PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23086925-0 2012 Bromodomain-containing protein 4 (BRD4) regulates RNA polymerase II serine 2 phosphorylation in human CD4+ T cells. Serine 68-74 bromodomain containing 4 Homo sapiens 0-32 23086925-0 2012 Bromodomain-containing protein 4 (BRD4) regulates RNA polymerase II serine 2 phosphorylation in human CD4+ T cells. Serine 68-74 bromodomain containing 4 Homo sapiens 34-38 23086925-2 2012 We used genome-wide chromatin immunoprecipitation sequencing in primary human CD4+ T cells to reveal that BRD4 co-localizes with Ser-2-phosphorylated Pol II (Pol II Ser-2) at both enhancers and promoters of active genes. Serine 129-132 bromodomain containing 4 Homo sapiens 106-110 23086925-2 2012 We used genome-wide chromatin immunoprecipitation sequencing in primary human CD4+ T cells to reveal that BRD4 co-localizes with Ser-2-phosphorylated Pol II (Pol II Ser-2) at both enhancers and promoters of active genes. Serine 165-168 bromodomain containing 4 Homo sapiens 106-110 23086925-4 2012 A large number of JQ1-disrupted BRD4 binding regions exhibited diacetylated H4 (lysine 5 and -8) and H3K27 acetylation (H3K27ac), which correlated with the presence of histone acetyltransferases and deacetylases. Lysine 80-86 bromodomain containing 4 Homo sapiens 32-36 23086925-7 2012 Our findings suggest that BRD4-driven Pol II phosphorylation at serine 2 plays an important role in regulating lineage-specific gene transcription in human CD4+ T cells. Serine 64-70 bromodomain containing 4 Homo sapiens 26-30