PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23006064-3 2012 We describe herein the discovery of arylidene thioxothiazolidinone as a scaffold for potent Tdp1 inhibitors based on an initial tyrphostin lead compound 8. Tyrphostins 128-138 tyrosyl-DNA phosphodiesterase 1 Homo sapiens 92-96