PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22764579-2	2012	In this study, the co-expression enzyme of human recombinant CYPOR, CYPb5 and CYP2D6.1 or CYP2D6.10 with the Bac-to-Bac system in baculovirus-infected insect cells was used to study the catalytical activity to imipramine metabolism and stereoselective metabolism of propranolol.	Propranolol	266-277	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	78-84	
22764579-2	2012	In this study, the co-expression enzyme of human recombinant CYPOR, CYPb5 and CYP2D6.1 or CYP2D6.10 with the Bac-to-Bac system in baculovirus-infected insect cells was used to study the catalytical activity to imipramine metabolism and stereoselective metabolism of propranolol.	Propranolol	266-277	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	90-96	
22764579-9	2012	Both of CYP2D6.1 and CYP2D6.10 produced more hydroxyl propranolol from the R-(+)-isomer than from the S-(-)-isomer while there was no obvious difference for N-desisopropylation propranolol production between R-(+)- and S-(-)- isomer.	Propranolol	54-65	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	8-14	
22764579-9	2012	Both of CYP2D6.1 and CYP2D6.10 produced more hydroxyl propranolol from the R-(+)-isomer than from the S-(-)-isomer while there was no obvious difference for N-desisopropylation propranolol production between R-(+)- and S-(-)- isomer.	Propranolol	54-65	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	21-27