PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22509028-4 2012 We report that BRD4 is an atypical kinase that binds to the carboxyl-terminal domain (CTD) of RNA polymerase II and directly phosphorylates its serine 2 (Ser2) sites both in vitro and in vivo under conditions where other CTD kinases are inactive. serine 2 144-152 bromodomain containing 4 Homo sapiens 15-19