PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22451348-6 2012 Using this model, we assessed the effects of the inflammatory cytokine interleukin-1alpha (IL-1alpha), several bioactive sphingolipids and all-trans retinoic acid (RA) on ceramide levels in the SC. Ceramides 171-179 interleukin 1 alpha Homo sapiens 91-100 22451348-7 2012 Whereas treatment with IL-1alpha (at 10 nM) significantly down-regulated ceramide levels, treatment with sphingosylphosphorylcholine (at 50 microM) or sphingosine-1-phosphate (at 10 or 20 microM) distinctly up-regulated ceramide levels. Ceramides 73-81 interleukin 1 alpha Homo sapiens 23-32 22451348-7 2012 Whereas treatment with IL-1alpha (at 10 nM) significantly down-regulated ceramide levels, treatment with sphingosylphosphorylcholine (at 50 microM) or sphingosine-1-phosphate (at 10 or 20 microM) distinctly up-regulated ceramide levels. Ceramides 220-228 interleukin 1 alpha Homo sapiens 23-32