PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22263894-2 2012 They are produced by oxidation of arachidonic acid (AA) by cyclooxygenases (COX-1 and COX-2) followed by metabolism of endoperoxide intermediates by terminal PG synthases. Arachidonic Acid 34-50 mitochondrially encoded cytochrome c oxidase II Homo sapiens 86-91