PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22221104-4	2012	KEY FINDINGS: The results demonstrated that the 5-HT(1A) agonist 8-OH-DPAT (s.c.) induced reductions in duration of LORR at 0.1, 0.5 and 1.0 mg/kg (P < 0.01), and prolongation of LORR latency at 0.5 and 1.0 mg/kg (s.c., P < 0.01) in pentobarbital (45 mg/kg, i.p.	8-Hydroxy-2-(di-n-propylamino)tetralin	65-74	5-hydroxytryptamine (serotonin) receptor 1A	Mus musculus	48-55	
22221104-6	2012	This effect of 8-OH-DPAT was antagonized either by 5-HT(1A) antagonist p-MPPI (5 mg/kg, i.p.)	8-Hydroxy-2-(di-n-propylamino)tetralin	15-24	5-hydroxytryptamine (serotonin) receptor 1A	Mus musculus	51-58	
22221104-12	2012	On the other hand, spinosin inhibited 8-OH-DPAT-induced hypothermia, which has been generally attributed to the activation of somatodendritic 5-HT(1A) autoreceptors in mice.	8-Hydroxy-2-(di-n-propylamino)tetralin	38-47	5-hydroxytryptamine (serotonin) receptor 1A	Mus musculus	142-149	
22221104-13	2012	CONCLUSIONS: Based on our previous results and the present data, it should be presumed that presynaptic 5-HT(1A) autoreceptor mechanisms may be involved in the inhibitory effect of spinosin on 8-OH-DPAT-induced hypothermia and also in the potentiating effect of spinosin on pentobarbital-induced LORR in mice.	8-Hydroxy-2-(di-n-propylamino)tetralin	193-202	5-hydroxytryptamine (serotonin) receptor 1A	Mus musculus	104-111