PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22185590-6	2011	Further, direct incubation of physiological concentrations of leucine and its metabolites alpha-Ketoisocaproic acid (KIC) and beta-hydroxy-methylbuteric acid (HMB) with recombinant human SIRT1 enzyme resulted in 30 to 50% increase of SIRT1 activity (p < 0.05).	Leucine	62-69	sirtuin 1	Homo sapiens	187-192	
22185590-6	2011	Further, direct incubation of physiological concentrations of leucine and its metabolites alpha-Ketoisocaproic acid (KIC) and beta-hydroxy-methylbuteric acid (HMB) with recombinant human SIRT1 enzyme resulted in 30 to 50% increase of SIRT1 activity (p < 0.05).	Leucine	62-69	sirtuin 1	Homo sapiens	234-239