PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21962117-2 2011 NOX/NADPH oxidases generate reactive oxygen species and NOX1, NOX2 and NOX4 isoforms are expressed in kidney and require association with subunit p22phox (encoded by the CYBA gene). Reactive Oxygen Species 28-51 NADPH oxidase 1 Homo sapiens 56-60 21962117-2 2011 NOX/NADPH oxidases generate reactive oxygen species and NOX1, NOX2 and NOX4 isoforms are expressed in kidney and require association with subunit p22phox (encoded by the CYBA gene). Reactive Oxygen Species 28-51 cytochrome b-245 alpha chain Homo sapiens 146-153 21962117-2 2011 NOX/NADPH oxidases generate reactive oxygen species and NOX1, NOX2 and NOX4 isoforms are expressed in kidney and require association with subunit p22phox (encoded by the CYBA gene). Reactive Oxygen Species 28-51 cytochrome b-245 alpha chain Homo sapiens 170-174 21962117-5 2011 The aim of the present investigation was to test whether functional single nucleotide polymorphisms (SNPs) in genes involved in the generation of NADPH-dependent O2 - (-675 T A in CYBA, unregistered) and in glutathione metabolism (-129 C T in GCLC [rs17883901] and -65 T C in GPX3 [rs8177412]) confer susceptibility to renal disease in type 1 diabetes patients. NADP 146-151 cytochrome b-245 alpha chain Homo sapiens 182-186 21962117-5 2011 The aim of the present investigation was to test whether functional single nucleotide polymorphisms (SNPs) in genes involved in the generation of NADPH-dependent O2 - (-675 T A in CYBA, unregistered) and in glutathione metabolism (-129 C T in GCLC [rs17883901] and -65 T C in GPX3 [rs8177412]) confer susceptibility to renal disease in type 1 diabetes patients. NADP 146-151 glutamate-cysteine ligase catalytic subunit Homo sapiens 247-251 21962117-5 2011 The aim of the present investigation was to test whether functional single nucleotide polymorphisms (SNPs) in genes involved in the generation of NADPH-dependent O2 - (-675 T A in CYBA, unregistered) and in glutathione metabolism (-129 C T in GCLC [rs17883901] and -65 T C in GPX3 [rs8177412]) confer susceptibility to renal disease in type 1 diabetes patients. NADP 146-151 glutathione peroxidase 3 Homo sapiens 282-286 21962117-5 2011 The aim of the present investigation was to test whether functional single nucleotide polymorphisms (SNPs) in genes involved in the generation of NADPH-dependent O2 - (-675 T A in CYBA, unregistered) and in glutathione metabolism (-129 C T in GCLC [rs17883901] and -65 T C in GPX3 [rs8177412]) confer susceptibility to renal disease in type 1 diabetes patients. Glutathione 209-220 glutamate-cysteine ligase catalytic subunit Homo sapiens 247-251 21962117-5 2011 The aim of the present investigation was to test whether functional single nucleotide polymorphisms (SNPs) in genes involved in the generation of NADPH-dependent O2 - (-675 T A in CYBA, unregistered) and in glutathione metabolism (-129 C T in GCLC [rs17883901] and -65 T C in GPX3 [rs8177412]) confer susceptibility to renal disease in type 1 diabetes patients. Glutathione 209-220 glutathione peroxidase 3 Homo sapiens 282-286