PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21909943-5 2011 In accordance with previous results in breast cancer cells (Choi et al., 2010), the knockdown of GIPC reduced ROS production in response to IGF-1 in colon cancer cells. Reactive Oxygen Species 110-113 GIPC PDZ domain containing family member 1 Homo sapiens 97-101 21909943-7 2011 Taken together, these data suggest that GIPC is involved in IGF-1 signaling leading to ZNF143 expression through the regulation of ROS production, which may play a role for colon cancer tumorigenesis. Reactive Oxygen Species 131-134 GIPC PDZ domain containing family member 1 Homo sapiens 40-44