PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21904878-5 2011 When beta-cells were exposed to a high concentration of glucose (25 mM), which stimulates insulin secretion, exe-4-induced cAMP formation declined gradually as exposure time was increased. Cyclic AMP 123-127 insulin Homo sapiens 90-97 21904878-7 2011 HNMPA was able to further increase the exe-4-induced insulin secretion when beta-cells were exposed to high glucose for 18 h. Treatment of beta-cells with insulin significantly decreased exe-4-induced cAMP formation in a dose-dependent manner. Cyclic AMP 201-205 insulin Homo sapiens 53-60 21904878-7 2011 HNMPA was able to further increase the exe-4-induced insulin secretion when beta-cells were exposed to high glucose for 18 h. Treatment of beta-cells with insulin significantly decreased exe-4-induced cAMP formation in a dose-dependent manner. Cyclic AMP 201-205 insulin Homo sapiens 155-162