PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21892977-4 2011 Rationales for use of vasopressin in septic shock are as follows: first, a deficiency of vasopressin in septic shock; second, low-dose vasopressin infusion improves blood pressure, decreases requirements for norepinephrine and improves renal function; and third, a recent randomized, controlled, concealed trial of vasopressin versus norepinephrine (VASST) suggests low-dose vasopressin may decrease mortality of less severe septic shock. Norepinephrine 208-222 arginine vasopressin Homo sapiens 22-33 21892977-4 2011 Rationales for use of vasopressin in septic shock are as follows: first, a deficiency of vasopressin in septic shock; second, low-dose vasopressin infusion improves blood pressure, decreases requirements for norepinephrine and improves renal function; and third, a recent randomized, controlled, concealed trial of vasopressin versus norepinephrine (VASST) suggests low-dose vasopressin may decrease mortality of less severe septic shock. Norepinephrine 334-348 arginine vasopressin Homo sapiens 22-33 21892977-7 2011 There was potential benefit in the prospectively defined stratum of patients with less severe septic shock (5 to 14 mug/minute norepinephrine at randomization): vasopressin may have lowered mortality compared with norepinephrine (26% versus 36%, respectively, P = 0.04 within stratum). Norepinephrine 127-141 arginine vasopressin Homo sapiens 161-172 21892977-15 2011 In conclusion, low-dose vasopressin may be effective in patients who have less severe septic shock already receiving norepinephrine (such as patients with modest norepinephrine infusion (5 to 15 mug/minute) or low serum lactate levels). Norepinephrine 117-131 arginine vasopressin Homo sapiens 24-35 21892977-15 2011 In conclusion, low-dose vasopressin may be effective in patients who have less severe septic shock already receiving norepinephrine (such as patients with modest norepinephrine infusion (5 to 15 mug/minute) or low serum lactate levels). Norepinephrine 162-176 arginine vasopressin Homo sapiens 24-35