PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21884783-0	2011	High plasma thiocyanate levels in smokers are a key determinant of thiol oxidation induced by myeloperoxidase.	Sulfhydryl Compounds	67-72	myeloperoxidase	Homo sapiens	94-109	
21884783-2	2011	We hypothesized that smokers would have a high level of thiocyanate (SCN(-)), a preferred substrate for MPO, which in turn would predispose to thiol oxidation, an established independent risk factor for atherosclerosis.	Sulfhydryl Compounds	143-148	myeloperoxidase	Homo sapiens	104-107	
21884783-3	2011	In this study it is shown that on exposure to MPO/H(2)O(2), thiols on plasma proteins from nonsmokers were increasingly oxidized with increasing added SCN(-) concentrations.	Sulfhydryl Compounds	60-66	myeloperoxidase	Homo sapiens	46-49	
21884783-5	2011	When plasma from smokers and nonsmokers was exposed to MPO/H(2)O(2)-stimulated oxidation, a strong positive correlation (r=0.8139, P<0.0001) between the extent of thiol oxidation and the plasma SCN(-) concentrations was observed.	Sulfhydryl Compounds	166-171	myeloperoxidase	Homo sapiens	55-58	
21884783-7	2011	These data indicate that plasma SCN(-) levels are a key determinant of the extent of thiol oxidation on plasma proteins induced by MPO, and implicate HOSCN as an important mediator of inflammation-induced oxidative damage to proteins in smokers.	Sulfhydryl Compounds	85-90	myeloperoxidase	Homo sapiens	131-134