PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21881044-3 2011 Here, as one remarkable example, studies using a novel and highly selective pharmacologic inhibitor of the spleen tyrosine kinase Syk [PRT060318; 2-((1R,2S)-2-aminocyclohexylamino)-4-(m-tolylamino)pyrimidine-5-carboxamide] coupled with genetic experiments, demonstrate that Syk inhibition ameliorates both the acute and chronic responses to vascular injury without affecting hemostasis. 2-(2-aminocyclohexylamino)-4-(m-tolylamino)pyrimidine-5-carboxamide 135-144 spleen tyrosine kinase Mus musculus 130-133 21881044-3 2011 Here, as one remarkable example, studies using a novel and highly selective pharmacologic inhibitor of the spleen tyrosine kinase Syk [PRT060318; 2-((1R,2S)-2-aminocyclohexylamino)-4-(m-tolylamino)pyrimidine-5-carboxamide] coupled with genetic experiments, demonstrate that Syk inhibition ameliorates both the acute and chronic responses to vascular injury without affecting hemostasis. 2-(2-aminocyclohexylamino)-4-(m-tolylamino)pyrimidine-5-carboxamide 135-144 spleen tyrosine kinase Mus musculus 274-277