PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21821736-0 2011 Q172H replacement overcomes effects on the metabolism of cyclophosphamide and efavirenz caused by CYP2B6 variant with Arg262. efavirenz 78-87 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 98-104 21821736-1 2011 There are a number of reports indicating that CYP2B6*6 (c.516G>T and c.785A>G) is responsible for decreased clearance of efavirenz (EFV), although increased disposition of cyclophosphamide (CPA) in individuals with this polymorphism was observed. efavirenz 138-141 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 46-52