PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2161750-4 1990 At low concentrations (10-100 pg/ml) TGF beta enhanced 1,25-dihydroxyvitamin D3-dependent production of osteoclast-like cells, while at higher concentrations TGF beta was inhibitory. Calcitriol 55-79 transforming growth factor, beta 1 Mus musculus 37-45 2161750-6 1990 Antibodies directed against TGF beta significantly reduced the generation of osteoclast-like cells in 1,25-dihydroxyvitamin D3-treated cultures, indicating the contribution of endogenous TGF beta activity. Calcitriol 102-126 transforming growth factor, beta 1 Mus musculus 28-36 2161750-6 1990 Antibodies directed against TGF beta significantly reduced the generation of osteoclast-like cells in 1,25-dihydroxyvitamin D3-treated cultures, indicating the contribution of endogenous TGF beta activity. Calcitriol 102-126 transforming growth factor, beta 1 Mus musculus 187-195 2161750-7 1990 TGF beta also enhanced the accumulation of prostaglandin E2 (PGE2) in a dose-dependent manner. Dinoprostone 43-59 transforming growth factor, beta 1 Mus musculus 0-8 2161750-7 1990 TGF beta also enhanced the accumulation of prostaglandin E2 (PGE2) in a dose-dependent manner. Dinoprostone 61-65 transforming growth factor, beta 1 Mus musculus 0-8 2161750-9 1990 It is, thus, suggested that PG activity, probably PGE2, mediates the enhancing effect of low TGF beta concentrations and is required for the generation of osteoclast-like cells in this system. Prostaglandins 28-30 transforming growth factor, beta 1 Mus musculus 93-101 2161750-9 1990 It is, thus, suggested that PG activity, probably PGE2, mediates the enhancing effect of low TGF beta concentrations and is required for the generation of osteoclast-like cells in this system. Dinoprostone 50-54 transforming growth factor, beta 1 Mus musculus 93-101