PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21404072-0 2011 Effect of UDP-glucuronosyltransferase 2B15 polymorphism on bisphenol A glucuronidation. bisphenol A 59-70 UDP glucuronosyltransferase family 2 member B15 Homo sapiens 10-42 21404072-1 2011 Bisphenol A (BPA) is one of a number of potential endocrine-disrupting chemicals, which are metabolized mainly by UDP-glucuronosyltransferase 2B15 (UGT2B15) in humans. bisphenol A 0-11 UDP glucuronosyltransferase family 2 member B15 Homo sapiens 114-146 21404072-1 2011 Bisphenol A (BPA) is one of a number of potential endocrine-disrupting chemicals, which are metabolized mainly by UDP-glucuronosyltransferase 2B15 (UGT2B15) in humans. bisphenol A 0-11 UDP glucuronosyltransferase family 2 member B15 Homo sapiens 148-155 21404072-1 2011 Bisphenol A (BPA) is one of a number of potential endocrine-disrupting chemicals, which are metabolized mainly by UDP-glucuronosyltransferase 2B15 (UGT2B15) in humans. bisphenol A 13-16 UDP glucuronosyltransferase family 2 member B15 Homo sapiens 114-146 21404072-1 2011 Bisphenol A (BPA) is one of a number of potential endocrine-disrupting chemicals, which are metabolized mainly by UDP-glucuronosyltransferase 2B15 (UGT2B15) in humans. bisphenol A 13-16 UDP glucuronosyltransferase family 2 member B15 Homo sapiens 148-155 21404072-6 2011 However, the K (m), V (max), and CL (int) values of UGT2B15.3, UGT2B15.4, UGT2B15.6, and UGT2B15.7 having L86S, T352I, and/or K523T substitution(s) for BPA glucuronidation were comparable to those of UGT2B15.1. bisphenol A 224-227 UDP glucuronosyltransferase family 2 member B15 Homo sapiens 124-131 21404072-6 2011 However, the K (m), V (max), and CL (int) values of UGT2B15.3, UGT2B15.4, UGT2B15.6, and UGT2B15.7 having L86S, T352I, and/or K523T substitution(s) for BPA glucuronidation were comparable to those of UGT2B15.1. bisphenol A 224-227 UDP glucuronosyltransferase family 2 member B15 Homo sapiens 135-142 21404072-6 2011 However, the K (m), V (max), and CL (int) values of UGT2B15.3, UGT2B15.4, UGT2B15.6, and UGT2B15.7 having L86S, T352I, and/or K523T substitution(s) for BPA glucuronidation were comparable to those of UGT2B15.1. bisphenol A 224-227 UDP glucuronosyltransferase family 2 member B15 Homo sapiens 135-142 21404072-6 2011 However, the K (m), V (max), and CL (int) values of UGT2B15.3, UGT2B15.4, UGT2B15.6, and UGT2B15.7 having L86S, T352I, and/or K523T substitution(s) for BPA glucuronidation were comparable to those of UGT2B15.1. bisphenol A 224-227 UDP glucuronosyltransferase family 2 member B15 Homo sapiens 135-142 21404072-6 2011 However, the K (m), V (max), and CL (int) values of UGT2B15.3, UGT2B15.4, UGT2B15.6, and UGT2B15.7 having L86S, T352I, and/or K523T substitution(s) for BPA glucuronidation were comparable to those of UGT2B15.1. bisphenol A 224-227 UDP glucuronosyltransferase family 2 member B15 Homo sapiens 135-142 21404072-7 2011 These findings suggest that D85Y substitution in UGT2B15 decreases enzymatic function and that the polymorphic alleles of UGT2B15 are closely associated with variations in the metabolism and toxicity of BPA. bisphenol A 203-206 UDP glucuronosyltransferase family 2 member B15 Homo sapiens 49-56 21404072-7 2011 These findings suggest that D85Y substitution in UGT2B15 decreases enzymatic function and that the polymorphic alleles of UGT2B15 are closely associated with variations in the metabolism and toxicity of BPA. bisphenol A 203-206 UDP glucuronosyltransferase family 2 member B15 Homo sapiens 122-129