PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21092747-0 2011 p53 activation mediates polyglutamine-expanded ataxin-3 upregulation of Bax expression in cerebellar and pontine nuclei neurons. polyglutamine 24-37 ataxin 3 Mus musculus 47-55 21092747-1 2011 Spinocerebellar ataxia type 3 (SCA3) is an autosomal dominant neurodegenerative disorder caused by polyglutamine-expanded ataxin-3. polyglutamine 99-112 ataxin 3 Mus musculus 0-29 21092747-1 2011 Spinocerebellar ataxia type 3 (SCA3) is an autosomal dominant neurodegenerative disorder caused by polyglutamine-expanded ataxin-3. polyglutamine 99-112 ataxin 3 Mus musculus 31-35 21092747-1 2011 Spinocerebellar ataxia type 3 (SCA3) is an autosomal dominant neurodegenerative disorder caused by polyglutamine-expanded ataxin-3. polyglutamine 99-112 ataxin 3 Mus musculus 122-130 21092747-3 2011 Polyglutamine-expanded ataxin-3-Q79 caused apoptotic death of cerebellar and pontine nuclei neurons by upregulating mRNA expression of pro-apoptotic Bax and activating mitochondria-mediated apoptotic cascade. polyglutamine 0-13 ataxin 3 Mus musculus 23-31 21092747-10 2011 Our results suggest that polyglutamine-expanded ataxin-3 upregulates mRNA expression of Bax and PUMA and causes apoptotic death of affected neurons by enhancing phosphorylation and transcriptional activity of p53. polyglutamine 25-38 ataxin 3 Mus musculus 48-56