PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2107492-0 1990 2-Aminopurine abolishes EGF- and TPA-stimulated pp33 phosphorylation and c-fos induction without affecting the activation of protein kinase C. Epidermal Growth Factor (EGF) and Tetradecanoyl Phorbol Acetate (TPA) initiate signalling cascades in C3H 10T1/2 fibroblasts by primarily activating distinct protein kinases, the EGF receptor tyrosine kinase and protein kinase C respectively; there is no signal crossover at the initiation of signalling. Tetradecanoylphorbol Acetate 33-36 ret proto-oncogene Homo sapiens 326-350