PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21051590-4 2011 The first and rate-limiting step in steroidogenesis is the conversion of cholesterol to pregnenolone by a single enzyme, P450scc (CYP11A1), but this enzymatically complex step is subject to multiple regulatory mechanisms, yielding finely tuned quantitative regulation. Pregnenolone 88-100 cytochrome P450 family 11 subfamily A member 1 Homo sapiens 121-128 21051590-4 2011 The first and rate-limiting step in steroidogenesis is the conversion of cholesterol to pregnenolone by a single enzyme, P450scc (CYP11A1), but this enzymatically complex step is subject to multiple regulatory mechanisms, yielding finely tuned quantitative regulation. Pregnenolone 88-100 cytochrome P450 family 11 subfamily A member 1 Homo sapiens 130-137