PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20966033-1 2011 Heme oxygenase-1 (HO-1) induction by hemin or Panhematin protects against experimental pancreatitis. Hemin 37-42 heme oxygenase 1 Homo sapiens 0-16 20966033-1 2011 Heme oxygenase-1 (HO-1) induction by hemin or Panhematin protects against experimental pancreatitis. Hemin 37-42 heme oxygenase 1 Homo sapiens 18-22 20966033-1 2011 Heme oxygenase-1 (HO-1) induction by hemin or Panhematin protects against experimental pancreatitis. Hemin 46-56 heme oxygenase 1 Homo sapiens 0-16 20966033-1 2011 Heme oxygenase-1 (HO-1) induction by hemin or Panhematin protects against experimental pancreatitis. Hemin 46-56 heme oxygenase 1 Homo sapiens 18-22 20966033-2 2011 As a preclinical first step toward determining whether HO-1 upregulation is a viable target in acute pancreatitis (AP) patients, we tested the hypothesis that HO-1 expression in peripheral blood mononuclear cell (PBMC) subsets of hospitalized patients with mild AP is upregulated then normalizes upon recovery and that cells from AP patients have the potential to upregulate their HO-1 ex vivo if exposed to Panhematin. Hemin 408-418 heme oxygenase 1 Homo sapiens 159-163 20966033-2 2011 As a preclinical first step toward determining whether HO-1 upregulation is a viable target in acute pancreatitis (AP) patients, we tested the hypothesis that HO-1 expression in peripheral blood mononuclear cell (PBMC) subsets of hospitalized patients with mild AP is upregulated then normalizes upon recovery and that cells from AP patients have the potential to upregulate their HO-1 ex vivo if exposed to Panhematin. Hemin 408-418 heme oxygenase 1 Homo sapiens 159-163 20966033-6 2011 Panhematin induced HO-1 in ex vivo cultured AP PBMCs more readily than in HC or VC PBMCs. Hemin 0-10 heme oxygenase 1 Homo sapiens 19-23