PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20542014-5 2010 We report that rapamycin (2.5muM), significantly increases Abeta generation in murine neuron-like cells (N2a) transfected with the human "Swedish" mutant amyloid precursor protein (APP). Sirolimus 15-24 amyloid beta (A4) precursor protein Mus musculus 59-64 20542014-9 2010 injected Tg2576 Abeta-overproducing transgenic mice with rapamycin (3mg/kg/day) for 2weeks. Sirolimus 57-66 amyloid beta (A4) precursor protein Mus musculus 16-21 20542014-10 2010 We found increased Abeta levels associated with decreased sAPP-alpha at an average rapamycin plasma concentration of 169.7+/-23.5ng/mL by high performance liquid chromatography (HPLC). Sirolimus 83-92 amyloid beta (A4) precursor protein Mus musculus 19-24