PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 204321-1 1978 The use of perchloric acid and water for the extraction of CEA from tumour and foetal tissues has been investigated. Perchloric Acid 11-26 CEA cell adhesion molecule 3 Homo sapiens 59-62 204321-1 1978 The use of perchloric acid and water for the extraction of CEA from tumour and foetal tissues has been investigated. Water 31-36 CEA cell adhesion molecule 3 Homo sapiens 59-62 204321-2 1978 In the case of tumour, lower recoveries of CEA were obtained from perchloric acid extracts than from aqueous extracts of the same tissue. Perchloric Acid 66-81 CEA cell adhesion molecule 3 Homo sapiens 43-46 204321-3 1978 CEA has also been extracted with 3M KCl solution from insoluble perchloric acid residues of tumour homogenates and cancer patients" serum. Potassium Chloride 36-39 CEA cell adhesion molecule 3 Homo sapiens 0-3 204321-3 1978 CEA has also been extracted with 3M KCl solution from insoluble perchloric acid residues of tumour homogenates and cancer patients" serum. Perchloric Acid 64-79 CEA cell adhesion molecule 3 Homo sapiens 0-3 204321-4 1978 Whilst a large proportion of CEA activity recovered from tumour was associated with the perchloric acid residue, the corresponding amounts from serum were very small. Perchloric Acid 88-103 CEA cell adhesion molecule 3 Homo sapiens 29-32 204321-5 1978 CEA elution volumes for each extract, obtained by assay of Sephadex G-200 column fractions, showed significant heterogeneity in molecular size. sephadex 59-67 CEA cell adhesion molecule 3 Homo sapiens 0-3 204321-6 1978 The purified CEA pools also showed quantitative variations in the binding profiles on Con A-Sepharose. Sepharose 92-101 CEA cell adhesion molecule 3 Homo sapiens 13-16 204321-7 1978 It has been shown that perchloric acid modifies the carbohydrate in CEA, thus altering its Con A-binding properties. Perchloric Acid 23-38 CEA cell adhesion molecule 3 Homo sapiens 68-71 204321-7 1978 It has been shown that perchloric acid modifies the carbohydrate in CEA, thus altering its Con A-binding properties. Carbohydrates 52-64 CEA cell adhesion molecule 3 Homo sapiens 68-71