PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20349048-9 2010 Finally, it was observed that the nitric oxide (NO) anti-inflammatory effects on ICAM-1 expression appear to be indirectly mediated by HO-1 activation, since the inhibition of HO-1 prevented the inhibitory effect of the NO donor (S-nitroso-N-acetylpenicillamine) on LPS-induced ICAM-1 expression. S-Nitroso-N-Acetylpenicillamine 230-261 heme oxygenase 1 Homo sapiens 135-139 20349048-9 2010 Finally, it was observed that the nitric oxide (NO) anti-inflammatory effects on ICAM-1 expression appear to be indirectly mediated by HO-1 activation, since the inhibition of HO-1 prevented the inhibitory effect of the NO donor (S-nitroso-N-acetylpenicillamine) on LPS-induced ICAM-1 expression. S-Nitroso-N-Acetylpenicillamine 230-261 heme oxygenase 1 Homo sapiens 176-180