PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20177148-9 2010 Moreover, LPA-induced alpha-SMA expression was abrogated by treatment with the ERK inhibitor U0126 or the phosphoinositide-3-kinase inhibitor LY294002, but not the PLC inhibitor U73122. lysophosphatidic acid 10-13 mitogen-activated protein kinase 1 Homo sapiens 79-82 20177148-11 2010 These results suggest that cancer-secreted LPA induces differentiation of hASCs to cancer-associated fibroblasts through multiple signaling pathways involving Rho kinase, ERK, PLC, and phosphoinositide-3-kinase. lysophosphatidic acid 43-46 mitogen-activated protein kinase 1 Homo sapiens 171-174