PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20154146-2 2010 We identified the human OGFOD1 protein as a novel stress granule component that regulates the phosphorylation of eIF2alpha and the resumption of translation in cells recovering from arsenite-induced stress. arsenite 182-190 eukaryotic translation initiation factor 2A Homo sapiens 113-122 20154146-4 2010 Overexpression of OGFOD1 led to increased abundance of phosphorylated eIF2alpha, both in unstressed cells and in cells exposed to arsenite-induced stress, and to accelerated apoptosis during stress. arsenite 130-138 eukaryotic translation initiation factor 2A Homo sapiens 70-79 20154146-7 2010 These findings argue that OGFOD1 plays important proapoptotic roles in the regulation of translation and HRI-mediated phosphorylation of eIF2alpha in cells subjected to arsenite-induced stress. arsenite 169-177 eukaryotic translation initiation factor 2A Homo sapiens 137-146