PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20154087-8	2010	We found that celastrol also induced reactive oxygen species (ROS) generation, and ROS sequestration inhibited celastrol-induced expression of CHOP and DR5, and consequent sensitization to TRAIL.	Reactive Oxygen Species	83-86	DNA damage inducible transcript 3	Homo sapiens	143-147	
20154087-9	2010	Overall, our results demonstrate that celastrol can potentiate the apoptotic effects of TRAIL through down-regulation of cell survival proteins and up-regulation of death receptors via the ROS-mediated up-regulation of CHOP pathway.	Reactive Oxygen Species	189-192	DNA damage inducible transcript 3	Homo sapiens	219-223