PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20144704-1 2010 To assess the functions of the three human MutT-type enzymes, MTH1, MTH2, and NUDT5, mutation induction by an oxidized form of dGTP, 8-hydroxy-2"-deoxyguanosine 5"-triphosphate (8-OH-dGTP; 7,8-dihydro-8-oxo-2"-deoxyguanosine 5"-triphosphate), was examined using human 293T cells treated with their specific siRNAs. deoxyguanosine triphosphate 127-131 nudix hydrolase 1 Homo sapiens 62-66 20144704-6 2010 These results indicate that all three of the human MTH1, MTH2, and NUDT5 proteins act as a defense against the mutagenesis induced by oxidized dGTP. deoxyguanosine triphosphate 143-147 nudix hydrolase 1 Homo sapiens 51-55