PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20132841-2	2010	CsA inhibits isomerase activity of cellular-encoded cyclophilin proteins, of which cyclophilin A (CypA) in particular is required for HCV replication.	Cyclosporine	0-3	peptidylprolyl isomerase A	Homo sapiens	98-102	
20132841-7	2010	Importantly, the NS5A-CypA interactions were sensitive to CsA in a dose-responsive manner and an isomerase mutant of CypA interacted with NS5A less efficiently than wild-type CypA.	Cyclosporine	58-61	peptidylprolyl isomerase A	Homo sapiens	22-26	
20132841-7	2010	Importantly, the NS5A-CypA interactions were sensitive to CsA in a dose-responsive manner and an isomerase mutant of CypA interacted with NS5A less efficiently than wild-type CypA.	Cyclosporine	58-61	peptidylprolyl isomerase A	Homo sapiens	117-121	
20132841-7	2010	Importantly, the NS5A-CypA interactions were sensitive to CsA in a dose-responsive manner and an isomerase mutant of CypA interacted with NS5A less efficiently than wild-type CypA.	Cyclosporine	58-61	peptidylprolyl isomerase A	Homo sapiens	117-121	
20132841-8	2010	These findings correlate the anti-HCV properties of CsA with an ability of the compound to disrupt NS5A-CypA interactions in vitro and in vivo, whilst providing the basis for development of assay platforms suitable to screen compound libraries for novel inhibitors of the NS5A-CypA interaction.	Cyclosporine	52-55	peptidylprolyl isomerase A	Homo sapiens	104-108	
20132841-8	2010	These findings correlate the anti-HCV properties of CsA with an ability of the compound to disrupt NS5A-CypA interactions in vitro and in vivo, whilst providing the basis for development of assay platforms suitable to screen compound libraries for novel inhibitors of the NS5A-CypA interaction.	Cyclosporine	52-55	peptidylprolyl isomerase A	Homo sapiens	277-281