PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20128802-6 2010 KEY RESULTS: In oxaliplatin-treated CHK2 KO cells, accelerated apoptosis was accompanied by attenuated p53 stabilization and p21(WAF-1) up-regulation correlating with increased Bax expression, cytochrome c release and elevated caspase activity. Oxaliplatin 16-27 tumor protein p53 Homo sapiens 103-106 20128802-8 2010 This "uncoupling" of p53 stabilization and Bax up-regulation in CHK2 KO cells suggested oxaliplatin-induced apoptosis was due to a p53-independent response. Oxaliplatin 88-99 tumor protein p53 Homo sapiens 21-24 20128802-8 2010 This "uncoupling" of p53 stabilization and Bax up-regulation in CHK2 KO cells suggested oxaliplatin-induced apoptosis was due to a p53-independent response. Oxaliplatin 88-99 tumor protein p53 Homo sapiens 131-134