PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20128155-1 2009 OBJECTIVE: The objective of this study was to investigate the effect of simvastatin on TLR4,TNF-alpha and IL-6 expression in the myocardium and its relation to left ventricular (LV) remodelling in a rat model of myocardial infarction (MI) and to investigate the mechanism by which simvastatin improves LV remodelling in rats after MI. Simvastatin 72-83 interleukin 6 Rattus norvegicus 106-110 20128155-6 2009 The expression of TLR4, TNF-alpha and IL-6 in the myocardium significantly increased in the MI group and simvastatin markedly inhibits the expression of TLR4, TNF-alpha, and IL-6 in the myocardium after MI. Simvastatin 105-116 interleukin 6 Rattus norvegicus 174-178 20128155-8 2009 Both in the MI group and the simvastatin group,TLR4 protein positively related to LVEDD and to the levels of TNF-alpha and IL-6 in the myocardium, respectively. Simvastatin 29-40 interleukin 6 Rattus norvegicus 123-127