PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20122921-2	2010	Recently, chronic psychosocial stress as animal model of depression has been shown to stimulate CREB transcriptional activity in the brain; this stimulation was prevented by treatment with the antidepressant imipramine, which inhibits both noradrenaline and serotonin reuptake.	Serotonin	258-267	cAMP responsive element binding protein 1	Mus musculus	96-100	
20122921-3	2010	However, it was unknown whether the selective inhibition of serotonin reuptake is sufficient for inhibition of stress-induced CREB activation, as it is for the clinical antidepressant effect.	Serotonin	60-69	cAMP responsive element binding protein 1	Mus musculus	126-130