PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20101100-1 2010 BACKGROUND: Protein tyrosine phosphatase (PTP)- 1B, encoded by the PTPN1 gene, negatively regulates insulin signaling by dephosphorylating the phosphotyrosine residues of the insulin receptor kinase activation segment. Phosphotyrosine 143-158 insulin Homo sapiens 100-107