PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20071449-1 2010 We have reported previously that the hepatic heme-regulated inhibitor (HRI)-eukaryotic initiation factor 2 alpha (eIF2 alpha) kinase is activated in acute heme-deficient states, resulting in translational shut-off of global hepatic protein synthesis, including phenobarbital (PB)-mediated induction of CYP2B enzymes in rats. Phenobarbital 276-278 cytochrome P450 family 2 subfamily B member 7, pseudogene Homo sapiens 302-307