PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20019189-0	2010	Iron-dependent regulation of MDM2 influences p53 activity and hepatic carcinogenesis.	Iron	0-4	tumor protein p53	Homo sapiens	45-48	
20019189-4	2010	Iron dependent regulation of MDM2/p53 was confirmed ex-vivo in human monocytes, by manipulation of iron pool and in a genetic model of iron deficiency, leading to modulation of p53 target genes involved in the antioxidant response and apoptosis.	Iron	0-4	tumor protein p53	Homo sapiens	34-37	
20019189-4	2010	Iron dependent regulation of MDM2/p53 was confirmed ex-vivo in human monocytes, by manipulation of iron pool and in a genetic model of iron deficiency, leading to modulation of p53 target genes involved in the antioxidant response and apoptosis.	Iron	0-4	tumor protein p53	Homo sapiens	177-180	
20019189-4	2010	Iron dependent regulation of MDM2/p53 was confirmed ex-vivo in human monocytes, by manipulation of iron pool and in a genetic model of iron deficiency, leading to modulation of p53 target genes involved in the antioxidant response and apoptosis.	Iron	99-103	tumor protein p53	Homo sapiens	34-37	
20019189-5	2010	Iron status influenced p53 ubiquitination and degradation rate, and the MDM2 inhibitor nutlin increased p53 levels in iron-depleted cells.	Iron	0-4	tumor protein p53	Homo sapiens	23-26	
20019189-5	2010	Iron status influenced p53 ubiquitination and degradation rate, and the MDM2 inhibitor nutlin increased p53 levels in iron-depleted cells.	Iron	118-122	tumor protein p53	Homo sapiens	104-107	
20019189-7	2010	The MDM2 -309T > G promoter polymorphism, determining increased MDM2 and lower p53 activity, was associated with higher risk of hepatocarcinoma in cirrhotic patients with hemochromatosis, and with HFE mutations in patients with hepatocarcinoma without hemochromatosis, suggesting an interaction between MDM2 and iron in the pathogenesis of hepatocarcinoma.	Iron	315-319	tumor protein p53	Homo sapiens	82-85	
20019189-8	2010	In conclusion, iron status influences p53 activity and antioxidant response by modulating MDM2 expression.	Iron	15-19	tumor protein p53	Homo sapiens	38-41