PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19919601-1 2010 Administration of melatonin to rodents decreases the incidence of tumorigenesis initiated by benzo[a]pyrene or 7,12-dimethylbenz[a]anthracene, which requires bioactivation by cytochrome P450 enzymes, such as CYP1A1, CYP1A2 and CYP1B1, to produce carcinogenic metabolites. Benzo(a)pyrene 93-107 cytochrome P450 family 1 subfamily B member 1 Homo sapiens 227-233