PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19509473-1	2009	Clinical studies have demonstrated that aldosterone receptor antagonists do improve the survival of patients with chronic heart diseases and in vitro studies have shown that canrenone blocks the proinflammatory effect of aldosterone in mononucler leukocytes (MNL).	Canrenone	174-183	nuclear receptor subfamily 3 group C member 2	Homo sapiens	40-60	
19509473-2	2009	The aim of the study was to compare, in the model of human MNL, the effect of potassium-sparing diuretics amiloride and canrenone, on the protein expression of p22phox, a NADPH-oxidase system subunit, that is a principal marker of production of superoxide anions.	Potassium	78-87	cytochrome b-245 alpha chain	Homo sapiens	160-167	
19509473-2	2009	The aim of the study was to compare, in the model of human MNL, the effect of potassium-sparing diuretics amiloride and canrenone, on the protein expression of p22phox, a NADPH-oxidase system subunit, that is a principal marker of production of superoxide anions.	Canrenone	120-129	cytochrome b-245 alpha chain	Homo sapiens	160-167	
19509473-2	2009	The aim of the study was to compare, in the model of human MNL, the effect of potassium-sparing diuretics amiloride and canrenone, on the protein expression of p22phox, a NADPH-oxidase system subunit, that is a principal marker of production of superoxide anions.	Superoxides	245-262	cytochrome b-245 alpha chain	Homo sapiens	160-167	
19509473-5	2009	The experiments showed that aldosterone (10(-8) M) enhances the protein expression of p22phox and that its effect is reversed by co-incubation with canrenone (10(-6) M), while incubation with amiloride (10(-6) M) reduced the prooxidative effect of aldosterone at a significantly lower extent than canrenone.	Aldosterone	28-39	cytochrome b-245 alpha chain	Homo sapiens	86-93	
19509473-5	2009	The experiments showed that aldosterone (10(-8) M) enhances the protein expression of p22phox and that its effect is reversed by co-incubation with canrenone (10(-6) M), while incubation with amiloride (10(-6) M) reduced the prooxidative effect of aldosterone at a significantly lower extent than canrenone.	Canrenone	148-157	cytochrome b-245 alpha chain	Homo sapiens	86-93	
19509473-5	2009	The experiments showed that aldosterone (10(-8) M) enhances the protein expression of p22phox and that its effect is reversed by co-incubation with canrenone (10(-6) M), while incubation with amiloride (10(-6) M) reduced the prooxidative effect of aldosterone at a significantly lower extent than canrenone.	Amiloride	192-201	cytochrome b-245 alpha chain	Homo sapiens	86-93	
19509473-5	2009	The experiments showed that aldosterone (10(-8) M) enhances the protein expression of p22phox and that its effect is reversed by co-incubation with canrenone (10(-6) M), while incubation with amiloride (10(-6) M) reduced the prooxidative effect of aldosterone at a significantly lower extent than canrenone.	Aldosterone	248-259	cytochrome b-245 alpha chain	Homo sapiens	86-93	
19509473-5	2009	The experiments showed that aldosterone (10(-8) M) enhances the protein expression of p22phox and that its effect is reversed by co-incubation with canrenone (10(-6) M), while incubation with amiloride (10(-6) M) reduced the prooxidative effect of aldosterone at a significantly lower extent than canrenone.	Canrenone	297-306	cytochrome b-245 alpha chain	Homo sapiens	86-93	
19509473-9	2009	The addition of aldosterone-receptor antagonist canrenone produced a higher inhibition than sodium channel blocker amiloride on the effect of aldosterone on p22phox protein expression.	Canrenone	48-57	cytochrome b-245 alpha chain	Homo sapiens	157-164	
19509473-9	2009	The addition of aldosterone-receptor antagonist canrenone produced a higher inhibition than sodium channel blocker amiloride on the effect of aldosterone on p22phox protein expression.	Amiloride	115-124	cytochrome b-245 alpha chain	Homo sapiens	157-164	
19509473-9	2009	The addition of aldosterone-receptor antagonist canrenone produced a higher inhibition than sodium channel blocker amiloride on the effect of aldosterone on p22phox protein expression.	Aldosterone	16-27	cytochrome b-245 alpha chain	Homo sapiens	157-164