PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19465513-3 2009 In this study, we determined the effect of DMF on platelet-derived growth factor (PDGF)-BB- and TNFalpha-induced asthma-relevant cytokines and NF-kappaB activation by primary human asthmatic and nonasthmatic airway smooth muscle cells (ASMC). Dimethyl Fumarate 43-46 tumor necrosis factor Homo sapiens 96-104 19465513-7 2009 TNFalpha-induced eotaxin, RANTES, and IL-6 as well as PDGF-BB-induced IL-6 expression was inhibited by DMF and by dexamethasone from asthmatic and nonasthmatic ASMC, but the combination of both drugs showed no glucocorticoid sparing effect in either of the two groups. Dimethyl Fumarate 103-106 tumor necrosis factor Homo sapiens 0-8 19465513-9 2009 DMF inhibited TNFalpha-induced NF-kappaB p65 phosphorylation, NF-kappaB nuclear entry, and NF-kappaB-DNA complex formation, whereas PDGF-BB appeared not to activate NF-kappaB within 60 min. Dimethyl Fumarate 0-3 tumor necrosis factor Homo sapiens 14-22