PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18829552-0 2008 ATM and the Mre11-Rad50-Nbs1 complex respond to nucleoside analogue-induced stalled replication forks and contribute to drug resistance. Nucleosides 48-58 ATM serine/threonine kinase Homo sapiens 0-3 18829552-0 2008 ATM and the Mre11-Rad50-Nbs1 complex respond to nucleoside analogue-induced stalled replication forks and contribute to drug resistance. Nucleosides 48-58 MRE11 homolog, double strand break repair nuclease Homo sapiens 12-17 18829552-0 2008 ATM and the Mre11-Rad50-Nbs1 complex respond to nucleoside analogue-induced stalled replication forks and contribute to drug resistance. Nucleosides 48-58 RAD50 double strand break repair protein Homo sapiens 18-23 18829552-0 2008 ATM and the Mre11-Rad50-Nbs1 complex respond to nucleoside analogue-induced stalled replication forks and contribute to drug resistance. Nucleosides 48-58 nibrin Homo sapiens 24-28 18829552-1 2008 The Mre11-Rad50-Nbs1 complex and autophosphorylated Ser(1981)-ATM are involved in recognizing and repairing DNA damage, such as double-strand breaks (DSB). Serine 52-55 ATM serine/threonine kinase Homo sapiens 62-65 18829552-5 2008 Cellular responses to both DSBs and stalled replication forks are marked by H2AX phosphorylation on Ser(139) (gamma-H2AX), which forms nuclear foci at sites of DNA damage. Serine 100-103 H2A.X variant histone Homo sapiens 76-80 18829552-5 2008 Cellular responses to both DSBs and stalled replication forks are marked by H2AX phosphorylation on Ser(139) (gamma-H2AX), which forms nuclear foci at sites of DNA damage. Serine 100-103 H2A.X variant histone Homo sapiens 116-120 18829552-7 2008 Using gamma-H2AX as a marker for changes in chromatin structure, we show that Mre11, Rad50, Nbs1, and phosphorylated ATM respond to nucleoside analogue-induced stalled replication forks by forming nuclear foci that colocalize with gamma-H2AX within 2 hours. Nucleosides 132-142 H2A.X variant histone Homo sapiens 12-16 18829552-7 2008 Using gamma-H2AX as a marker for changes in chromatin structure, we show that Mre11, Rad50, Nbs1, and phosphorylated ATM respond to nucleoside analogue-induced stalled replication forks by forming nuclear foci that colocalize with gamma-H2AX within 2 hours. Nucleosides 132-142 MRE11 homolog, double strand break repair nuclease Homo sapiens 78-83 18829552-7 2008 Using gamma-H2AX as a marker for changes in chromatin structure, we show that Mre11, Rad50, Nbs1, and phosphorylated ATM respond to nucleoside analogue-induced stalled replication forks by forming nuclear foci that colocalize with gamma-H2AX within 2 hours. Nucleosides 132-142 RAD50 double strand break repair protein Homo sapiens 85-90 18829552-7 2008 Using gamma-H2AX as a marker for changes in chromatin structure, we show that Mre11, Rad50, Nbs1, and phosphorylated ATM respond to nucleoside analogue-induced stalled replication forks by forming nuclear foci that colocalize with gamma-H2AX within 2 hours. Nucleosides 132-142 nibrin Homo sapiens 92-96 18829552-7 2008 Using gamma-H2AX as a marker for changes in chromatin structure, we show that Mre11, Rad50, Nbs1, and phosphorylated ATM respond to nucleoside analogue-induced stalled replication forks by forming nuclear foci that colocalize with gamma-H2AX within 2 hours. Nucleosides 132-142 ATM serine/threonine kinase Homo sapiens 117-120 18829552-7 2008 Using gamma-H2AX as a marker for changes in chromatin structure, we show that Mre11, Rad50, Nbs1, and phosphorylated ATM respond to nucleoside analogue-induced stalled replication forks by forming nuclear foci that colocalize with gamma-H2AX within 2 hours. Nucleosides 132-142 H2A.X variant histone Homo sapiens 237-241 18829552-9 2008 Deficiencies in ATM, Mre11, or Rad50 led to a 2- to 5-fold increase in clonogenic sensitization to gemcitabine, whereas Nbs1 and H2AX deficiency did not affect reproductive growth. gemcitabine 99-110 ATM serine/threonine kinase Homo sapiens 16-19 18829552-9 2008 Deficiencies in ATM, Mre11, or Rad50 led to a 2- to 5-fold increase in clonogenic sensitization to gemcitabine, whereas Nbs1 and H2AX deficiency did not affect reproductive growth. gemcitabine 99-110 MRE11 homolog, double strand break repair nuclease Homo sapiens 21-26 18829552-9 2008 Deficiencies in ATM, Mre11, or Rad50 led to a 2- to 5-fold increase in clonogenic sensitization to gemcitabine, whereas Nbs1 and H2AX deficiency did not affect reproductive growth. gemcitabine 99-110 RAD50 double strand break repair protein Homo sapiens 31-36