PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18691157-0	2008	Protective effect of paraoxonase-2 against endoplasmic reticulum stress-induced apoptosis is lost upon disturbance of calcium homoeostasis.	Calcium	118-125	paraoxonase 2	Homo sapiens	21-34	
18691157-2	2008	Addressing the cytoprotective functions of PON2, we observed that PON2 overexpression provided significant resistance to ER-stress-induced caspase 3 activation when the ER stress was induced by interference with protein modification (by tunicamycin or dithiothreitol), but not when ER stress was induced by disturbance of Ca(2+) homoeostasis (by thapsigargin or A23187).	Tunicamycin	237-248	paraoxonase 2	Homo sapiens	66-70	
18691157-2	2008	Addressing the cytoprotective functions of PON2, we observed that PON2 overexpression provided significant resistance to ER-stress-induced caspase 3 activation when the ER stress was induced by interference with protein modification (by tunicamycin or dithiothreitol), but not when ER stress was induced by disturbance of Ca(2+) homoeostasis (by thapsigargin or A23187).	Dithiothreitol	252-266	paraoxonase 2	Homo sapiens	66-70	
18691157-2	2008	Addressing the cytoprotective functions of PON2, we observed that PON2 overexpression provided significant resistance to ER-stress-induced caspase 3 activation when the ER stress was induced by interference with protein modification (by tunicamycin or dithiothreitol), but not when ER stress was induced by disturbance of Ca(2+) homoeostasis (by thapsigargin or A23187).	Thapsigargin	346-358	paraoxonase 2	Homo sapiens	66-70	
18691157-2	2008	Addressing the cytoprotective functions of PON2, we observed that PON2 overexpression provided significant resistance to ER-stress-induced caspase 3 activation when the ER stress was induced by interference with protein modification (by tunicamycin or dithiothreitol), but not when ER stress was induced by disturbance of Ca(2+) homoeostasis (by thapsigargin or A23187).	Calcimycin	362-368	paraoxonase 2	Homo sapiens	66-70	
18691157-4	2008	However, only tunicamycin and dithiothreitol resulted in increased PON2 mRNA and protein levels.	Tunicamycin	14-25	paraoxonase 2	Homo sapiens	67-71	
18691157-4	2008	However, only tunicamycin and dithiothreitol resulted in increased PON2 mRNA and protein levels.	Dithiothreitol	30-44	paraoxonase 2	Homo sapiens	67-71	
18691157-6	2008	In addition, thapsigargin and A23187 also induced PON2 protein degradation by a Ca(2+)-dependent calpain-mediated mechanism.	Thapsigargin	13-25	paraoxonase 2	Homo sapiens	50-54	
18691157-6	2008	In addition, thapsigargin and A23187 also induced PON2 protein degradation by a Ca(2+)-dependent calpain-mediated mechanism.	Calcimycin	30-36	paraoxonase 2	Homo sapiens	50-54