PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18606486-0	2008	Desipramine-induced apoptosis in human PC3 prostate cancer cells: activation of JNK kinase and caspase-3 pathways and a protective role of [Ca2+]i elevation.	Desipramine	0-11	mitogen-activated protein kinase 8	Homo sapiens	80-83	
18606486-6	2008	Immunoblotting data revealed that desipramine activated the phosphorylation of c-Jun NH2-terminal kinase (JNK), but not extracellular signal-regulated kinase (ERK) and p38 mitogen-activated protein kinase (MAPK).	Desipramine	34-45	mitogen-activated protein kinase 8	Homo sapiens	79-104	
18606486-6	2008	Immunoblotting data revealed that desipramine activated the phosphorylation of c-Jun NH2-terminal kinase (JNK), but not extracellular signal-regulated kinase (ERK) and p38 mitogen-activated protein kinase (MAPK).	Desipramine	34-45	mitogen-activated protein kinase 8	Homo sapiens	106-109	
18606486-9	2008	Immunoblotting data suggest that BAPTA/AM pretreatment enhanced desipramine-evoked JNK phosphorylation and caspase-3 cleavage.	Desipramine	64-75	mitogen-activated protein kinase 8	Homo sapiens	83-86	
18606486-10	2008	The results suggest that in PC3 cells, desipramine caused apoptosis via inducing JNK-associated caspase-3 activation, and [Ca2+]i rises may slow down or alleviate desipramine-induced cytotoxicity.	Desipramine	39-50	mitogen-activated protein kinase 8	Homo sapiens	81-84