PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18505519-3	1998	All-trans retinoic acid significantly decreased and increased the secretions of MMP-1 and TIMP-1 respectively, in a dose-dependent manner, from 10-7 m to 10-5 m. Entrapment of RA into CER vesicles potentiated its effect on MMP-1 and TIMP-1 secretions by HSF, independently of cell passages.	Tretinoin	10-23	interleukin 6	Homo sapiens	254-257	
18505519-3	1998	All-trans retinoic acid significantly decreased and increased the secretions of MMP-1 and TIMP-1 respectively, in a dose-dependent manner, from 10-7 m to 10-5 m. Entrapment of RA into CER vesicles potentiated its effect on MMP-1 and TIMP-1 secretions by HSF, independently of cell passages.	Tretinoin	176-178	interleukin 6	Homo sapiens	254-257	
18505519-4	1998	The extent of variations obtained on MMP-1 and TIMP-1 levels, when HSF culture medium was supplemented with 10-5 m RA, could be obtained using a 100-fold lower concentration of RA encapsulated into CER vesicles.	Tretinoin	177-179	interleukin 6	Homo sapiens	67-70	
18505519-6	1998	The rate of internalization of RA into HSF was increased when used in its CER encapsulated form.	Tretinoin	31-33	interleukin 6	Homo sapiens	39-42