PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18495890-2 2008 Using the camptothecin-induced DNA damage model in neurons, we previously showed that cyclin D1-associated cell cycle cyclin-dependent kinases (Cdks) (Cdk4/6) and p53 activation are two major events leading to activation of the mitochondrial apoptotic pathway. Camptothecin 10-22 tumor protein p53 Homo sapiens 163-166