PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18442489-1	2008	The attachment of biotin onto the biotin-dependent enzymes is catalysed by biotin protein ligase (BPL), also known as holocarboxylase synthase HCS in mammals.	Biotin	18-24	holocarboxylase synthetase	Homo sapiens	143-146	
18442489-1	2008	The attachment of biotin onto the biotin-dependent enzymes is catalysed by biotin protein ligase (BPL), also known as holocarboxylase synthase HCS in mammals.	Biotin	34-40	holocarboxylase synthetase	Homo sapiens	143-146	
18442489-3	2008	All mammalian biotin-enzymes are post-translationally biotinylated, and therefore activated, through the action of a single HCS.	Biotin	14-20	holocarboxylase synthetase	Homo sapiens	124-127	
18442489-5	2008	Defects in biotin metabolism, including HCS, give rise to multiple carboxylase deficiency (MCD).	Biotin	11-17	holocarboxylase synthetase	Homo sapiens	40-43