PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18425390-0	2008	Alterations of the K-ras and p53 genes in Tamoxifen-associated endometrial carcinoma.	Tamoxifen	42-51	tumor protein p53	Homo sapiens	29-32	
18425390-3	2008	The median duration of TAM exposure was significantly longer in patients with p53 mutations than those without p53 mutations (62 vs. 30 months, p=0.028).	Tamoxifen	23-26	tumor protein p53	Homo sapiens	78-81	
18425390-3	2008	The median duration of TAM exposure was significantly longer in patients with p53 mutations than those without p53 mutations (62 vs. 30 months, p=0.028).	Tamoxifen	23-26	tumor protein p53	Homo sapiens	111-114	
18425390-4	2008	Our observation suggests that prolonged TAM exposure may directly inactivate the p53 gene by acting as a mutagen in a significant fraction of TAM-associated endometrial carcinomas.	Tamoxifen	40-43	tumor protein p53	Homo sapiens	81-84	
18425390-4	2008	Our observation suggests that prolonged TAM exposure may directly inactivate the p53 gene by acting as a mutagen in a significant fraction of TAM-associated endometrial carcinomas.	Tamoxifen	142-145	tumor protein p53	Homo sapiens	81-84